Parenterally, as treatment of hypocalcemic tetany, hypocalcemia related to hypoparathyroidism, and hypocalcemia caused by rapid growth or pregnancy;
Treatment of hyperkalemia-induced cardiac toxicity, provided the patient is not receiving digitalis therapy; to decrease capillary permeability in allergic conditions, nonthrombocytopenic purpura, and exudative dermatoses, such as dermatitis herpetiformis, and for pruritus of eruptions caused by certain drugs;
Treatment of black widow spider bites to relieve muscle cramping; adjunctive treatment of rickets, osteomalacia, lead colic, and magnesium sulfate overdosage. Orally as a dietary supplement.
Essential for maintenance of the functional integrity of nervous, muscular, and skeletal systems and cell membrane and capillary permeability.
It is also an important activator in many enzymatic reactions and is essential to a number of physiologic processes, including transmission of nerve impulses; contraction of cardiac, smooth, and skeletal muscles; renal function; respiration; and blood coagulation. Calcium also plays regulatory roles in the release and storage of neurotransmitters and hormones, in the uptake and binding of amino acids, and in cyanocobalamin (vitamin B12 ) absorption and gastrin secretion. 1 g (10 mL) of calcium gluconate 10% contains 93 mg (4.65 mEq) calcium.