Induction of mid-trimester abortion.
Treatment of postpartum hemorrhage that has not responded to conventional therapy.
Test Dose IM (Adults): 100 mcg .
Abortifacient IM (Adults): 250 mcg every 1.5–3.5 hr depending upon uterine response; may be increased to 500 mcg if several doses of 250 mcg produce inadequate response (not to exceed 2 days of continuous therapy or total dose of 12 mg).
Causes uterine contractions by directly stimulating the myometrium.
Use Cautiously in:
CNS: dizziness, headache .
Resp: wheezing .
GI: diarrhea , nausea, vomiting , abdominal pain, cramps .
GU: uterine rupture.
Derm: flushing .
Misc: fever , chills, shivering.
Augments the effects of other oxytocic agents.
Therapeutic Classification: abortifacients
Pharmacologic Classification: oxytocics, prostaglandins
Absorption: Well absorbed following IM administration.
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