Adult: 400mg once a day. Single dose administration in the evening reduces nocturnal symptoms and helps to keep the patients complaint free during the day. However, in certain cases 400mg twice daily is recommended on the basis of the clinical response.
nausea , vomiting, epigastric pain, cephalalgia, irritability, insomnia, tachycardia, extrasystole, tachypnea and occassioinally hyperglycemia and albuminuria, may occur. If a potential oral overdose is established, the patient may present with severe arrhythmias and seizure these symptoms could be the first sign of an intoxication.
Adverse reactions may cause the withdrawl from treatment a lower dose rechallange may start only after the advice of a physician.