Dose depends on blood glucose, response, and many other factors
Use Cautiously in:
Endo: hypoglycemia .
Local: erythema, lipodystrophy , pruritis, swelling.
Misc: allergic reactions including anaphylaxis.
Therapeutic Classification: antidiabetics, hormones
Pharmacologic Classification: pancreatics
Absorption: Well absorbed from subcutaneous administration sites. Absorption rate is determined by type of insulin, injection site, volume of injectate, and other factors.
Distribution: Widely distributed.
Metabolism/Excretion: Metabolized by liver, spleen, kidney, and muscle.
Half-life: 5–6 min (prolonged in patients with diabetes; biologic half-life is 1–1.5 hr; ).
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