Concentrated regular insulin U-500:
Dose depends on blood glucose, response, and many other factors
Ketoacidosis — Regular (100 units/mL)Insulin Only
Treatment of Hyperkalemia
Use Cautiously in:
Endo: hypoglycemia .
Local: lipodystrophy, pruritus , erythema, swelling.
Misc: allergic reactions including anaphylaxis.
Therapeutic Classification: antidiabetics, hormones
Pharmacologic Classification: pancreatics
Absorption: Rapidly absorbed from subcutaneous administration sites. U-100 regular insulin is absorbed slightly more quickly than U-500.
Distribution: Identical to endogenous insulin.
Metabolism/Excretion: Metabolized by liver, spleen, kidney, and muscle.
Half-life: 30–60 min.
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