Adults:POUsual dose : 2 to 6 mg/day (range, 1 to 10 mg/day) in divided doses; largest dose at bedtime.
Initial dose: 1 to 2 mg/day in divided doses; increase gradually.
Insomnia Caused By Anxiety or Transient Situational Stress
Adults:PO 2 to 4 mg at bedtime.
Adults:IM 0.05 mg/kg at least 2 h before procedure (max, 4 mg).
Initial dose:IV 2 mg total or 0.044 mg/kg, whichever is smaller. Do not exceed in patients over 50 yr of age.
For increased lack of recall: 0.05 mg/kg (max, 4 mg), 15 to 20 min before procedure.
Adults:IV Recommended dose 4 mg given at rate of 2 mg/min. If seizures continue or recur after a 10- to 15-min observation period, an additional 4 mg IV may be administered slowly.
Tablets and oral solution
Administer prescribed dose without regard to meals but administer with food if GI upset occurs.
Tablets may be administered sublingually to patient who has difficulty swallowing tablets.
Use calibrated dropper to measure prescribed dose of concentrated oral solution. Add prescribed dose to a liquid (eg, juice, water, soda) or semisolid food (eg, applesauce, pudding); stir for a few seconds then immediately administer entire amount of mixture. Do not prepare and store doses for future use.
For IM or IV administration only. Not for intradermal, SC, or intra-arterial administration.
For IM administration, inject undiluted solution deeply into muscle.
For IV administration, dilute with equal volume of compatible solution (eg, sterile water for injection, sodium chloride injection or 5% dextrose injection). Do not shake vigorously to avoid air entrapment. Administer directly into a vein or into tubing of existing IV infusion at rate not exceeding 2 mg/min.
Do not administer if particulate matter, cloudiness, or discoloration is noted. Discard any unused solution. Do not save for future use.