Adults:PO Titrate dosage based on therapeutic response and tolerance. To reduce the incidence and severity of adverse reactions, use the lowest effective dose. Do not exceed a maximum of 10 mg/dose or 30 mg daily.
Adults:PO 5 mg 3 times daily. If no response, increase dosage to 10 mg 3 times daily. Continue uninterrupted for at least 12 wk before assessing for full therapeutic benefit (max, 30 mg/day).
Adults:PO 5 mg 4 times daily. Continue uninterrupted for at least 6 wk before assessing for full therapeutic benefit.
Adults:Ophthalmic solution Instill 1 to 2 drops in affected eye(s) up to 4 times daily. More concentrated solutions are sometimes used.
Adults:Ophthalmic gel Apply one-half inch ribbon in lower conjunctival sac of affected eye(s) once daily at bedtime.