Although the exact mechanism of tazarotene action is not known, studies have shown that the active form of the drug (tazarotenic acid) binds to all three members of the retinoic acid receptor (RAR) family: RARa, RARb, and RARg, but shows relative selectivity for RARb, and RARg and may modify gene expression. It also has affinity for RXR receptors.
This medication may make you more sensitive to the sun. Limit your time in the sun. Avoid tanning booths and sunlamps. Use sunscreen daily and wear protective clothing when outdoors. Tell your doctor right away if you get sunburned or have skin blisters/redness. Wait until your skin has completely recovered from a sunburn before using this medication. Weather extremes such as wind or cold may also be irritating to the skin.
Avoid electrolysis, waxing, and chemical depilatories for hair removal on the treated areas while using this product.
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
This medication must not be used during pregnancy. It may harm an unborn baby. Discuss the use of reliable forms of birth control (such as condoms, birth control pills) with your doctor. If you become pregnant or think you may be pregnant, tell your doctor right away. Before starting this medication, women who could become pregnant should have a negative pregnancy test result within the last 2 weeks. This medication should be started during a normal menstrual period.
vitamin A products, hair perming solutions, other skin products with strong drying effects, skin products containing alcohol/lime/spice (such as shaving lotions, astringents such as calaminelotion, perfume), soaps/shampoos/cleansers that are medicated/abrasive.