Thiamine Deficiency (Beriberi)
Use Cautiously in:
Adverse reactions and side effects are extremely rare and are usually associated with IV administration or extremely large doses
CNS: restlessness , weakness.
EENT: tightness of the throat .
Resp: pulmonary edema , respiratory distress.
CV: vascular collapse , hypotension, vasodilation .
GI: GI bleeding , nausea.
Derm: cyanosis, pruritus , sweating, tingling , urticaria, warmth .
Misc: angioedema .
Therapeutic Classification: vitamins
Pharmacologic Classification: water soluble vitamins
Absorption: Well absorbed from the GI tract by an active process. Excessive amounts are not absorbed completely. Also well absorbed from IM sites.
Distribution: Widely distributed. Enters breast milk.
Metabolism/Excretion: Metabolized by the liver. Excess amounts are excreted unchanged by the kidneys.
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