Oral Oedema Adult: Initially, 40 mg daily in the morning, reduced to 20 mg daily according to response.
Max: 80 mg daily. Renal impairment: Severe: Avoid. Hepatic impairment: Use with caution. Oral Hypertension Adult: 20 mg daily as a single dose in the morning.
Renal impairment: Severe: Avoid.
Hepatic impairment: Use with caution.
Absorption: Rapid and well absorbed from GI tract. Peak plasma concentration: 1-2 hr. Distribution: Protein binding: 99%. Excretion: Excreted in urine as unchanged and glucuronide metabolite. Plasma half life: 5-8 hr.